Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrogen Bromide → 2-Bromo-1-(1-naphthalenyl)ethanone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrogen Bromide | HCID 260 | — |
| 반응물 | Chloroform | HCID 6212 | — |
| 반응물 | 1-Acetylnaphthalene | HCID 13663 | — |
| 촉매 | Copper bromide (CuBr2) | HCID 24611 | — |
| 용매 | Ethyl Acetate | HCID 8857 | — |
| 생성물 | 2-Bromo-1-(1-naphthalenyl)ethanone | HCID 3830513 | — |
반응 단계
Methyl 1-naphthyl ketone (10.1 g.), in 50 ml of a 1:1 mixture of chloroform and ethyl acetate is treated with 26.5 g. of copper (II) bromide. The resulting reaction mixture is heated under reflux with vigorous stirring until the evolution of hydrogen bromide ceases. When the reaction is complete the solvent is removed, ether is added and the copper (I) bromide is removed by filtration. Evaporation of the filtrate under reduced pressure yields crude bromomethyl 1-naphthyl ketone.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04150153 |
| 출처 데이터셋 | uspto-grants-1979_04 |
| ORD ID | ord-1489e7152d2f4faab50106df544efc62 |
| 출처 메모 | uspto-grants-1979_04 |