Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl Isocyanate → N-(3-methyl-5-isothiazolyl)-N'-methylurea
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl Isocyanate | HCID 12228 | — |
| 반응물 | 3-Methylisothiazol-5-amine | HCID 32307 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | N-(3-methyl-5-isothiazolyl)-N'-methylurea | HCID 23336007 | 54.5% |
반응 단계
Methylisocyanate (1.96 milliliters, 0.04 mole) was added dropwise to a thirty (30) milliliter solution of tetrahydrofuran (distilled from calcium hydride) containing the above mentioned 5-amino-3-methylisothiazole (5.0 grams, 0.04 mole), and then the resulting yellow solution was refluxed for 3 hours, during which time a white precipitate formed. The solution was cooled and filtered, giving 3.73 grams of 1-(3-methyl-5-isothiazolyl)-3-methylurea, also referred to as 3-methyl-5-N-methylureidoisothiazole.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04150226 |
| 출처 데이터셋 | uspto-grants-1979_04 |
| ORD ID | ord-4dabd8acaf6f44008abf1131372dba24 |
| 출처 메모 | uspto-grants-1979_04 |