Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1,3-Benzenedicarboxylic acid, 4-methyl-, 1,3-dimethyl ester → 4-Methylbenzene-1,3-dicarboxylic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1,3-Benzenedicarboxylic acid, 4-methyl-, 1,3-dimethyl ester | HCID 89971 | — |
| 반응물 | Lithium hydroxide, monohydrate | HCID 168937 | — |
| 용매 | Methanol tetrahydrofuran water | HCID 21892291 | — |
| 생성물 | 4-Methylbenzene-1,3-dicarboxylic acid | HCID 595750 | — |
반응 단계
A solution of 2-20 (1.5 g, 7.2 mmoles) in THF/MeOH/H2O (1:1:1) (36 ml) at room temperature was treated with LiOH.H2O (1.5 g, 36 mmoles). After stirring for 3 hours, the solvent was removed and the residue acidified with 1N HCl. This was extracted with EtOAc, and the extract was dried (MgSO4) and concentrated to give 2-21.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05648368 |
| 출처 데이터셋 | uspto-grants-1997_07 |
| ORD ID | ord-a4daebdea2f44a1488ff83b844dfc640 |
| 출처 메모 | uspto-grants-1997_07 |