Nitric Acid → 5-Nitronaphthalene-1,4-dione

HRID 267250

반응식

HRID 267250 반응식
[C:1]1(=[O:12])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[C:4](=[O:11])[CH:3]=[CH:2]1.S(=O)(=O)(O)O.S(=O)(=O)=O.[N+:22]([O-])([OH:24])=[O:23]>O>[N+:22]([C:6]1[CH:7]=[CH:8][CH:9]=[C:10]2[C:5]=1[C:4](=[O:11])[CH:3]=[CH:2][C:1]2=[O:12])([O-:24])=[O:23]

참가 물질

6

반응물 4

HCID 944Nitric AcidHCID 1118Sulfuric Acid2회HCID 85301,4-NaphthoquinoneHCID 24682Sulfur trioxide

생성물 1

HCID 123364025-Nitronaphthalene-1,4-dione

시약·촉매·용매 1

HCID 962Water용매

실험 절차

In the same apparatus as in Example 1, 10.0 g of 1,4-naphthoquinone was added to 40 g of fuming sulfuric acid of a sulfur trioxide content of 20 percent maintained at 0° to 5°C, then added thereto 30 g of a mixed acid consisting of 70 percent by weight of sulfuric acid, 25 percent by weight of nitric acid and 5 percent by weight of water dropwise over 1 hour while maintaining the reaction temperature at 15° to 20°C. The reaction mixture was maintained at 15° to 20°C for additional 3 hours and then processed in the same manner as in Example 6 to obtain 11.0 g of crude 5-nitro-1,4-naphthoquinone of a melting point of 153°C. The crude product was purified in the same manner as in Example 6 to obtain the same result as in Example 1.

후처리

  1. temperaturemaintained at 0° to 5°C
  2. additionadded
  3. temperaturewhile maintaining the reaction temperature at 15° to 20°C
  4. temperatureThe reaction mixture was maintained at 15° to 20°C for additional 3 hours

출처 및 근거

ORD 기록
ord-072de987dddc4c41bed24a1c298d1c6d
출처 데이터셋
uspto-grants-1976_03
특허 번호
US03941815

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