Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Toluene → Ethyl 4-(2-pyrimidinylimino)-1-piperidinecarboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Toluene | HCID 1140 | — |
| 반응물 | 2-Aminopyrimidine | HCID 7978 | — |
| 반응물 | Ethyl 4-oxo-1-piperidinecarboxylate | HCID 34767 | — |
| 촉매 | Acetic Acid | HCID 176 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | Ethyl 4-(2-pyrimidinylimino)-1-piperidinecarboxylate | HCID 21460901 | — |
반응 단계
A mixture of 34 parts of ethyl 4-oxo-1-piperidinecarboxylate, 20 parts of 2-pyrimidinamine, 8 drops of acetic acid and 90 parts of methylbenzene is stirred and refluxed for 28 hours with water-separator. The reaction mixture is evaporated, yielding 50 parts of ethyl 4-(2-pyrimidinylimino)-1-piperidinecarboxylate as a residue.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04151286 |
| 출처 데이터셋 | uspto-grants-1979_04 |
| ORD ID | ord-703b2da5f9a44fb3a4000f8a8b5801ac |
| 출처 메모 | uspto-grants-1979_04 |