Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Nitrobenzaldehyde → 2-Methyl-4-(3'-nitrophenyl)-1,4-dihydropyridine-3,5,6-tricarboxylic acid triethyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Nitrobenzaldehyde | HCID 7449 | — |
| 반응물 | Diethyl oxalacetate | HCID 66951 | — |
| 반응물 | 2-Butenoic acid, 3-amino-, ethyl ester, (2Z)- | HCID 643756 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 2-Methyl-4-(3'-nitrophenyl)-1,4-dihydropyridine-3,5,6-tricarboxylic acid triethyl ester | HCID 13399319 | 62% |
반응 단계
15 g of 3-nitrobenzaldehyde, 13 g of β-aminocrotonic acid ethyl ester and 19 g of oxalacetic acid diethyl ester in 60 ccs of ethanol are heated to the boil overnight. The green-yellow crystals obtained, in 62% yield, after cooling, melt at 123°.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US03943140 |
| 출처 데이터셋 | uspto-grants-1976_03 |
| ORD ID | ord-984de16bcd4b4bc9a5c0567941d3ef1f |
| 출처 메모 | uspto-grants-1976_03 |