Tryptamine → HCID 15083993, 화합물

HRID 267553

반응식

HRID 267553 반응식
[NH2:1][CH2:2][CH2:3][C:4]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[NH:6][CH:5]=1.[C:13](O)(=[O:19])[CH2:14][CH2:15][C:16]([CH3:18])=O>CCCCOCCO>[CH3:18][C:16]12[C:5]3[NH:6][C:7]4[C:12]([C:4]=3[CH2:3][CH2:2][N:1]1[C:13](=[O:19])[CH2:14][CH2:15]2)=[CH:11][CH:10]=[CH:9][CH:8]=4

참가 물질

4

반응물 2

HCID 1150TryptamineHCID 11579Levulinic Acid

생성물 1

HCID 15083993HCID 15083993, 화합물

시약·촉매·용매 1

HCID 81332-Butoxyethanol용매

실험 절차

Tryptamine (112.15 g.), levulinic acid (97.6 g., 85.6 ml.) and butyl cellosolve (1 liter) are refluxed under nitrogen for 16 hours and the solvent is removed. The residue is successively washed with water, dilute aqueous sodium hydroxide, water, dilute aqueous hydrochloric acid, water and dried. Trituration of the crude product, decomposition at 252°-262°C., with methanol, and then with benzene, and drying provides 120.4 g. of the title compound, decomposition at 259°-263°C.; λmaxKBr 3.09, 6.01, 6.17, 13.38 μ.

후처리

  1. customthe solvent is removed
  2. washThe residue is successively washed with water, dilute aqueous sodium hydroxide, water, dilute aqueous hydrochloric acid, water
  3. customdried
  4. dry with materialTrituration of the crude product, decomposition at 252°-262°C., with methanol, and then with benzene, and drying
  5. customprovides 120.4 g

출처 및 근거

ORD 기록
ord-57fe05309dae4472a9ac00f0582f7e80
출처 데이터셋
uspto-grants-1976_03
특허 번호
US03943148

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