Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-(2',4',5'-Triethoxybenzoyl)-trans-acrylic acid → Trepibutone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-(2',4',5'-Triethoxybenzoyl)-trans-acrylic acid | HCID 12353591 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | Trepibutone | HCID 5536 | — |
반응 단계
A mixture of 1.0 part by weight of 3-(2',4',5'-triethoxybenzoyl)-trans-acrylic acid, 50 parts by volume of methanol and 0.2 part by weight of 5% palladium-charcoal is subjected to catalytic reduction at 25°C under atmospheric pressure for 1 hour. After removal of the catalyst by filtration, the filtrate is evaporated and the residue is recrystallized from aqueous ethanol to give 0.85 part by weight of 3-(2',4',5'-triethoxybenzoyl)-propionic acid as pale yellow needles melting at 150°-151°C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US03943169 |
| 출처 데이터셋 | uspto-grants-1976_03 |
| ORD ID | ord-3a6b6ec22a71468d9a4d5454d9190e36 |
| 출처 메모 | uspto-grants-1976_03 |