Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methanol → 2-Amino-3-n-propoxy-5-methylpyrazine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methanol | HCID 887 | — |
| 반응물 | 2,3-Dichloropyrazine | HCID 78575 | — |
| 반응물 | 2-Amino-3-bromo-5-methylpyrazine | HCID 9899043 | — |
| 용매 | 1-Propanol | HCID 1031 | — |
| 생성물 | 2-Amino-3-n-propoxy-5-methylpyrazine | HCID 20528988 | — |
반응 단계
By replacing the 2,3-dichloropyrazine and anhydrous methanol used in Preparation 43 by equivalent quantities of the product of Step A and n-propanol and following the method described in Preparation 43, 2-amino-3-n-propoxy-5-methylpyrazine is obtained. The 2-amino group can be converted to the 2-hydroxy by the method described by Sharp et al, ibid., (see Route III) which when treated with phosphorus oxychloride by the method of Preparation 13, Step B, provides 2-chloro-3-n-propoxy-5-methylpyrazine.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US03946009 |
| 출처 데이터셋 | uspto-grants-1976_03 |
| ORD ID | ord-420b03f54d664c9d86948acaaa5b44d3 |
| 출처 메모 | uspto-grants-1976_03 |