Morpholine → 5-Bromo-3-morpholinopyrazin-2-amine

HRID 267951

반응식

[NH2:1][C:2]1[C:7](Br)=[N:6][C:5]([Br:9])=[CH:4][N:3]=1.[NH:10]1[CH2:15][CH2:14][O:13][CH2:12][CH2:11]1>>[NH2:1][C:2]1[C:7]([N:10]2[CH2:15][CH2:14][O:13][CH2:12][CH2:11]2)=[N:6][C:5]([Br:9])=[CH:4][N:3]=1

참가 물질

반응물 2

HCID 8083Morpholine

HCID 6200042-Amino-3,5-dibromopyrazine

생성물 1

HCID 167404415-Bromo-3-morpholinopyrazin-2-amine

실험 절차

2-Amino-3,5-dibromopyrazine is reacted with morpholine at 130° C. under pressure yielding 2-amino-3-morpholino-5-bromopyrazine.

출처 및 근거

ORD 기록: ord-b993021882dd4c128798b109602af068
출처 데이터셋: uspto-grants-1976_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US03946009

연결된 노트

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