Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrogen Bromide → 2-Bromo-4-trifluoromethylaniline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrogen Bromide | HCID 260 | — |
| 반응물 | 4-(Trifluoromethyl)aniline | HCID 9964 | — |
| 반응물 | Bromine | HCID 24408 | — |
| 촉매 | Iron | HCID 23925 | — |
| 생성물 | 2-Bromo-4-trifluoromethylaniline | HCID 93899 | — |
반응 단계
To 161.0 g of p-aminobenzotrifluoride and 10.0 g of iron filings is added, dropwise, with agitation at 35°-40°, 160.0 g of bromine, using a slow stream of nitrogen to sweep out the evolved hydrogen bromide. Subsequently, the mixture is agitated for an additional two hours and then distilled in vacuo to give 3-bromo-4-aminobenzotrifluoride.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US03946025 |
| 출처 데이터셋 | uspto-grants-1976_03 |
| ORD ID | ord-43f19edd3f3340d590cf99d0d5f9b7f4 |
| 출처 메모 | uspto-grants-1976_03 |