Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sulfuryl chloride → Ethyl 2-chloro-3-oxopentanoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sulfuryl chloride | HCID 24648 | — |
| 반응물 | Ethyl 3-oxovalerate | HCID 78656 | — |
| 용매 | Chloroform | HCID 6212 | — |
| 생성물 | Ethyl 2-chloro-3-oxopentanoate | HCID 12923424 | — |
반응 단계
Sulphuryl chloride (286 g.) was added dropwise to a solution of ethyl 3-oxopentanoate (300 g.) in chloroform (250 ml.) at 10°-15°. Following addition the mixture was stirred overnight at room temperature, heated under reflux for 0.5 hours and cooled. After washing with water, sodium bicarbonate and water, the solution was dried (sodium sulphate), concentrated, and fractionated to yield ethyl 2-chloro-3-oxopentanoate, b.p. 94°-96°/14 mm.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04151288 |
| 출처 데이터셋 | uspto-grants-1979_04 |
| ORD ID | ord-c5cafc11c6b1484381f814e313447934 |
| 출처 메모 | uspto-grants-1979_04 |