4-Methyl-3-nitroaniline → HCID 178428208, 화합물

HRID 268274

반응식

HRID 268274 반응식
[ClH:1].N([C:9]1[C:18]2[C:13](=[CH:14][CH:15]=[C:16]3[N:21]=[CH:20][NH:19][C:17]3=2)[N:12]=[C:11]([CH3:22])[CH:10]=1)C1C=CC=CC=1.[CH3:23][C:24]1[CH:30]=[CH:29][C:27]([NH2:28])=[CH:26][C:25]=1[N+:31]([O-:33])=[O:32]>C(O)C>[ClH:1].[CH3:23][C:24]1[CH:30]=[CH:29][C:27]([NH:28][C:9]2[C:18]3[C:13](=[CH:14][CH:15]=[C:16]4[N:21]=[CH:20][NH:19][C:17]4=3)[N:12]=[C:11]([CH3:22])[CH:10]=2)=[CH:26][C:25]=1[N+:31]([O-:33])=[O:32]

참가 물질

4

반응물 2

HCID 83904-Methyl-3-nitroanilineHCID 178428198HCID 178428198, 화합물

생성물 1

HCID 178428208HCID 178428208, 화합물

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

A mixture of 10.85 g. (0.05 m.) of the compound of Example I, C., 7.6 g. (0.05 m.) of 4-methyl-3-nitroaniline and 500 ml. of ethanol was refluxed overnight. The reaction mixture was concentrated in vacuo to give 38 g. of crude product. It was then dissolved in 6000 ml. of MeOH and filtered hot. The MeOH filtrate was concentrated in vacuo to yield 27 g., m.p. 344°-345°C.

후처리

  1. additionA mixture of 10.85 g
  2. concentrationThe reaction mixture was concentrated in vacuo
  3. customto give 38 g
  4. dissolutionIt was then dissolved in 6000 ml
  5. filtrationof MeOH and filtered hot
  6. concentrationThe MeOH filtrate was concentrated in vacuo
  7. customto yield 27 g

출처 및 근거

ORD 기록
ord-5a650ce85fff40e790f052503055eb84
출처 데이터셋
uspto-grants-1976_03
특허 번호
US03947434

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