Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ammonia → 2-Amino-1-(3-nitrophenyl)ethanol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ammonia | HCID 222 | — |
| 반응물 | Hydrogen Bromide | HCID 260 | — |
| 반응물 | m-Nitroacetophenone | HCID 8494 | — |
| 반응물 | Sodium borohydride | HCID 4311764 | — |
| 생성물 | 2-Amino-1-(3-nitrophenyl)ethanol | HCID 18628156 | — |
반응 단계
3-Nitroacetophenone is brominated in the α-position, the bromination product is reduced by means of sodium borohydride to the corresponding bromohydride and this is treated with ammonia. There is obtained rac.-α-(aminomethyl)-3-nitrobenzyl alcohol which melts at 107°-108° (softening from 105°) after crystallization from ethyl acetate-ether.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US03947456 |
| 출처 데이터셋 | uspto-grants-1976_03 |
| ORD ID | ord-43b11491cddd49dd992e9585706b5712 |
| 출처 메모 | uspto-grants-1976_03 |