Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sulfuric Acid → 2H-1-Benzopyran-6-ol, 3,4-dihydro-2-methoxy-2,5,7,8-tetramethyl-
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sulfuric Acid | HCID 1118 | — |
| 반응물 | Methyl vinyl ketone | HCID 6570 | — |
| 반응물 | Trimethyl orthoformate | HCID 9005 | — |
| 반응물 | Trimethylhydroquinone | HCID 12785 | — |
| 반응물 | 2-Methoxy-1,3-butadiene | HCID 99338 | — |
| 반응물 | 4-Hydroxy-2-Butanone | HCID 111509 | — |
| 반응물 | 2-Butanone, 4-methoxy- | HCID 138889 | — |
| 반응물 | 3,3-Dimethoxybut-1-ene | HCID 13028910 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 2H-1-Benzopyran-6-ol, 3,4-dihydro-2-methoxy-2,5,7,8-tetramethyl- | HCID 103763 | — |
반응 단계
In the manner described in Example 1, 3.80 g (25 mmol) samples of trimethylhydroquinone were treated in 25 ml of methanol, 5.0 ml of trimethyl orthoformate, and 0.10 ml of 36 N aqueous H2SO4 with 50 mmole portions of the following methyl vinyl ketone substitutes: a, 2-methoxybutadiene; b, 3-ketobutanol; c, 3,3-dimethoxybutene (contaminated with about 20 percent 2-methoxybutadiene); and d, 4-methoxy-2-butanone. The reactions were monitored by tlc. Reactions a,c and d were complete after 24 hr and were worked up and dried in the manner of Example 1 to give (±)-6-hydroxy-2-methoxy-2,5,7,8-tetramethylchroman. In reaction b, a>50 percent conversion to (±)-6-hydroxy-2-methoxy-2,5,7,8-tetramethylchroman was indicated by tlc.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US03947473 |
| 출처 데이터셋 | uspto-grants-1976_03 |
| ORD ID | ord-7499afe1cbc242abbe87599304411fec |
| 출처 메모 | uspto-grants-1976_03 |