Thionyl Chloride → 4-(3-Amino-3-oxoprop-1-en-2-yl)benzoyl chloride

HRID 268502노트

반응식

HRID 268502 반응식
S(Cl)([Cl:3])=O.[C:5]([C:8]1[CH:18]=[CH:17][C:11]([C:12](=[CH2:16])[C:13]([NH2:15])=[O:14])=[CH:10][CH:9]=1)(O)=[O:6]>>[Cl:3][C:5]([C:8]1[CH:18]=[CH:17][C:11]([C:12](=[CH2:16])[C:13]([NH2:15])=[O:14])=[CH:10][CH:9]=1)=[O:6]

참가 물질

3

반응물 2

HCID 24386Thionyl ChlorideHCID 21413842HCID 21413842, 화합물

생성물 1

HCID 214138224-(3-Amino-3-oxoprop-1-en-2-yl)benzoyl chloride

실험 절차

A mixture of 50 cc. of thionyl chloride and 0.05 moles of p-carboxyatropamide is heated at reflux on the steam-bath for 1/2 hour. The reaction mixture is concentrated in vacuo to give p-chlorocarbonylatropamide suitable for use in the following step.

후처리

  1. additionA mixture of 50 cc
  2. temperatureat reflux on the steam-bath for 1/2 hour
  3. concentrationThe reaction mixture is concentrated in vacuo

출처 및 근거

ORD 기록
ord-f2c810ecf6614f0890a0fcb34e724931
출처 데이터셋
uspto-grants-1976_03
특허 번호
US03947582

반응 노트

불러오는 중…