Acetyl chloride → Phenyl acetate
반응식
[O-:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:8](Cl)(=[O:10])[CH3:9]>CCOCC>[C:8]([O:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1)(=[O:10])[CH3:9]참가 물질
4
실험 절차
A vigorously stirred suspension of thallous phenoxide (5 g., 0.017 m.) in anhydrous ether (15 ml.) is treated dropwise with freshly distilled acetyl chloride (1.33 g., 0.017 m.) in anhydrous ether (3 ml.) over 5 mins. at such a rate that the exothermic reaction is controlled. The mixture is then stirred for 1 hour at room temperature, the precipitated thallous chloride removed by filtration through Celite and the solvent evaporated under vacuum. The residual colorless oil is distilled to give phenyl acetate, 2.27 g., 98%, b.p. 110°/58 mm.
후처리
- customat such a rate that the exothermic reaction
- customthe precipitated thallous chloride
- customremoved by filtration through Celite
- customthe solvent evaporated under vacuum
- distillationThe residual colorless oil is distilled
출처 및 근거
- ORD 기록
- ord-52748cb56aef414f9320e2f419e3bd4b
- 출처 데이터셋
- uspto-grants-1976_03
- 특허 번호
- US03947488
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