Ethanol → (1-Ethyl-1H-1,2,4-triazol-5-yl)methylammonium acetate

HRID 268598노트

반응식

HRID 268598 반응식
[CH2:1]([N:3]1[C:7]([CH:8]=[N:9][OH:10])=[N:6][CH:5]=[N:4]1)[CH3:2].[CH2:11]([OH:13])[CH3:12]>[OH-].[OH-].[Pd+2]>[C:11]([O-:10])(=[O:13])[CH3:12].[CH2:1]([N:3]1[C:7]([CH2:8][NH3+:9])=[N:6][CH:5]=[N:4]1)[CH3:2]

참가 물질

4

반응물 2

HCID 702EthanolHCID 136335088HCID 136335088, 화합물

생성물 1

HCID 86603337(1-Ethyl-1H-1,2,4-triazol-5-yl)methylammonium acetate

시약·촉매·용매 1

HCID 9942167Palladium hydroxide촉매

실험 절차

A mixture of 1-ethyl-1H-1,2,4-triazole-5-carbaldehyde oxime (6.17 g, 44 mmol), 10% palladium hydroxide on carbon (2.9 g) acetic acid (125 mL) and ethanol (125 mL) were stirred under an atmosphere of hydrogen for 14 hours. The reaction mixture was filtered and concentrated in vacuo to give the title compound (7.7 g) 1H-NMR (d6-DMSO) δ 1.32 (3H, t, J=7 Hz), 1.89 (3H, s), 3.89 (2H, br), 4.17 (2H, q, J=7 Hz), 7.80 (1H, s).

후처리

  1. filtrationThe reaction mixture was filtered
  2. concentrationconcentrated in vacuo

출처 및 근거

ORD 기록
ord-bab6cf9741d448c0be083d102f1aedc7
출처 데이터셋
uspto-grants-2008_11
특허 번호
US07446117B2

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