Piperidin-4-ol → 1-[3-(4-Morpholin-4-yl-but-1-ynyl)-benzyl]-piperidin-4-ol

HRID 268626

반응식

HRID 268626 반응식
[N:1]1([CH2:7][CH2:8][C:9]#[C:10][C:11]2[CH:12]=[C:13]([CH:16]=[CH:17][CH:18]=2)[CH:14]=O)[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1.[NH:19]1[CH2:24][CH2:23][CH:22]([OH:25])[CH2:21][CH2:20]1>>[N:1]1([CH2:7][CH2:8][C:9]#[C:10][C:11]2[CH:12]=[C:13]([CH:16]=[CH:17][CH:18]=2)[CH2:14][N:19]2[CH2:24][CH2:23][CH:22]([OH:25])[CH2:21][CH2:20]2)[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1

참가 물질

3

반응물 2

HCID 79341Piperidin-4-olHCID 224934723-(4-Morpholin-4-yl-but-1-ynyl)-benzaldehyde

생성물 1

HCID 102865791-[3-(4-Morpholin-4-yl-but-1-ynyl)-benzyl]-piperidin-4-ol

실험 절차

May be prepared analogously to Example 15 using the product of Example 10 and piperidin-4-ol.

출처 및 근거

ORD 기록
ord-89aade94fd2f408ab8221f1eacb46f68
출처 데이터셋
uspto-grants-2008_11
특허 번호
US07446104B2

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