Indole → (1,8-Diethyl-9-methyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetic acid

HRID 268680

반응식

HRID 268680 반응식
[CH2:1]([C:3]1([CH2:18][C:19]([OH:21])=[O:20])[C:8]2[NH:9][C:10]3[C:15]([C:7]=2[CH2:6][CH2:5][O:4]1)=[CH:14][CH:13]=[CH:12][C:11]=3[CH2:16][CH3:17])[CH3:2].N1C2C(=CC=CC=2)C=[CH:23]1>>[CH2:1]([C:3]1([CH2:18][C:19]([OH:21])=[O:20])[C:8]2[N:9]([CH3:23])[C:10]3[C:15]([C:7]=2[CH2:6][CH2:5][O:4]1)=[CH:14][CH:13]=[CH:12][C:11]=3[CH2:16][CH3:17])[CH3:2]

참가 물질

3

반응물 2

HCID 798IndoleHCID 3308Etodolac

생성물 1

HCID 14146242(1,8-Diethyl-9-methyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetic acid

실험 절차

Following the procedure of example 49.A. except using (1,8-Diethyl-1,3,4,9-tetrahydro-pyrano[3,4-b]indol-1-yl)-acetic acid as the indole component afforded the title compound as an oil.

출처 및 근거

ORD 기록
ord-b395e9aeba3140379afacfd0db63cf80
출처 데이터셋
uspto-grants-2008_11
특허 번호
US07446122B2

연결된 노트

불러오는 중…