Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Trifluoroacetic acid → Trifluoroacetic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Trifluoroacetic acid | HCID 6422 | — |
| 반응물 | tert-Butyl 4-(4-cyanophenoxy)piperidine-1-carboxylate | HCID 23019443 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | Trifluoroacetic acid | HCID 6422 | — |
| 생성물 | 4-(4-Piperidinyloxy)benzonitrile trifluoroacetate | HCID 17986319 | — |
반응 단계
4-[(1-tert-Butoxycarbonyl-4-piperidinyl)oxy]benzonitrile (D21) (6.83 g) was dissolved in DCM (30 ml) and TFA (30 ml) was added. The reaction was stirred at rt for 1 h and then evaporated to give the title compound (D22) as a yellow oil (7.15 g—TFA salt plus 1.3 equivalents of TFA).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07446103B2 |
| 출처 데이터셋 | uspto-grants-2008_11 |
| ORD ID | ord-3fd73069052141f396a29673fdef961f |
| 출처 메모 | uspto-grants-2008_11 |