HCID 45273676, 화합물 → HCID 59831679, 화합물

반응식

CO[C:3](=O)[NH:4][CH2:5][CH2:6][CH:7]([C:14]1[CH:22]=[C:21]2[C:17]([CH:18]=[CH:19][NH:20]2)=[CH:16][CH:15]=1)[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1.N1C2C(=CC(C(C3C=CC=CC=3)CCNC)=CC=2)C=C1>>[NH:20]1[C:21]2[C:17](=[CH:16][CH:15]=[C:14]([CH:7]([C:8]3[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=3)[CH2:6][CH2:5][NH:4][CH3:3])[CH:22]=2)[CH:18]=[CH:19]1

참가 물질

반응물 2

HCID 45273676HCID 45273676, 화합물

HCID 59831648HCID 59831648, 화합물

생성물 1

HCID 59831679HCID 59831679, 화합물수율 24%

실험 절차

[3-(1H-Indol-6-yl)-3-phenyl-propyl]-methyl-amine (110 mg, 24% yield) XVI was prepared as a hydrochloride salt from [3-(1H-indol-6-yl)-3-phenyl-propyl]-carbamic acid methylester (XV), using the procedure described for preparation of [3-(1H-indol-5-yl)-3-phenyl-propyl]-methyl-amine XI (see Example 2). MS (M+H)=265.

출처 및 근거

ORD 기록: ord-5d31efa0ecc64758bafcbfaa1867e54a
출처 데이터셋: uspto-grants-2008_11
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07446118B2

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