[3-(1H-Indol-7-yl)-3-phenyl-propyl]-methyl-amine → HCID 59831633, 화합물

반응식

[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[C:7]([CH:10]([C:16]3[CH:21]=[CH:20][CH:19]=[C:18]([O:22][CH3:23])[CH:17]=3)[CH2:11][C:12]([NH:14][CH3:15])=O)[CH:8]=2)[CH:3]=[CH:2]1.N1C2C(=CC=CC=2C(C2C=CC=CC=2)CCNC)C=C1>>[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[C:7]([CH:10]([C:16]3[CH:21]=[CH:20][CH:19]=[C:18]([O:22][CH3:23])[CH:17]=3)[CH2:11][CH2:12][NH:14][CH3:15])[CH:8]=2)[CH:3]=[CH:2]1

참가 물질

반응물 2

HCID 17747555[3-(1H-Indol-7-yl)-3-phenyl-propyl]-methyl-amine

HCID 59831810HCID 59831810, 화합물

생성물 1

HCID 59831633HCID 59831633, 화합물수율 94%

실험 절차

[3-(1H-Indol-6-yl)-3-(3-methoxy-phenyl)-propyl]-methyl-amine XXXIII (100 mg, 94% yield) was prepared as a hydrochloride salt from 3-(1H-indol-6-yl)-3-(3-methoxy-phenyl)-N-methyl-propionamide using the procedure described for [3-(1H-Indol-7-yl)-3-phenyl-propyl]-methyl-amine XX (see Example 4). MS (M+H)=295.

출처 및 근거

ORD 기록: ord-14bd8159e1e14ff0ba570fd3d277a51a
출처 데이터셋: uspto-grants-2008_11
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07446118B2

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