(4-Methoxyphenyl)boronic acid → 3-(1H-Indol-6-yl)-3-(4-methoxy-phenyl)-propionic acid methyl ester
반응식
B(O)(O)[C:2]1[CH:3]=[CH:4][C:5]([O:8][CH3:9])=[CH:6][CH:7]=1.[CH3:12][O:13][C:14](=[O:34])[CH2:15][CH:16]([C:25]1[CH:33]=[C:32]2[C:28]([CH:29]=[CH:30][NH:31]2)=[CH:27][CH:26]=1)C1C=CC=C(OC)C=1>>[CH3:12][O:13][C:14](=[O:34])[CH2:15][CH:16]([C:25]1[CH:33]=[C:32]2[C:28]([CH:29]=[CH:30][NH:31]2)=[CH:27][CH:26]=1)[C:2]1[CH:3]=[CH:4][C:5]([O:8][CH3:9])=[CH:6][CH:7]=1참가 물질
3
실험 절차
3-(1H-Indol-6-yl)-3-(4-methoxy-phenyl)-propionic acid methyl ester XXXIV (0.51 g, 66% yield) was prepared from 4-methoxy boronic acid using the procedure described for preparation of 3-(1H-indol-6-yl)-3-(3-methoxy-phenyl)-propionic acid methyl ester XXXI (see Example 7).
출처 및 근거
- ORD 기록
- ord-cb4a7514948740aa86727a264170c5a2
- 출처 데이터셋
- uspto-grants-2008_11
- 특허 번호
- US07446118B2