Methyl isothiocyanate → N-methyl-N'-[2-(3-isoxazolylmethoxy)ethyl]thiourea

HRID 26882노트

반응식

HRID 26882 반응식
Cl[CH2:2][C:3]1[CH:7]=[CH:6][O:5][N:4]=1.ClCC[O:11][CH2:12][C:13]1C=CO[N:14]=1.[CH3:18][N:19]=[C:20]=[S:21]>>[CH3:18][NH:19][C:20]([NH:14][CH2:13][CH2:12][O:11][CH2:2][C:3]1[CH:7]=[CH:6][O:5][N:4]=1)=[S:21]

참가 물질

4

반응물 3

HCID 11167Methyl isothiocyanateHCID 49130253-(Chloromethyl)-1,2-oxazoleHCID 205576623-(2-Chloroethoxymethyl)isoxazole

생성물 1

HCID 20557841N-methyl-N'-[2-(3-isoxazolylmethoxy)ethyl]thiourea

실험 절차

By the procedure of Example 38, 3-chloromethylisoxazole is converted to 3-(2-chloroethoxymethyl)isoxazole which is then reacted with methyl isothiocyanate to give N-methyl-N'-[2-(3-isoxazolylmethoxy)ethyl]thiourea.

출처 및 근거

ORD 기록
ord-2b2a48b030b34b38981b703253276e2c
출처 데이터셋
uspto-grants-1979_04
특허 번호
US04151288

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