3-(3-Methoxy-1H-indazol-4-yl)-3-phenyl-acrylic acid ethyl ester → 3-(3-Methoxy-1H-indazol-4-yl)-N-methyl-3-phenyl-acrylamide
반응식
C([O:3][C:4](=O)[CH:5]=[C:6]([C:13]1[CH:21]=[CH:20][CH:19]=[C:18]2[C:14]=1[C:15]([O:22][CH3:23])=[N:16][NH:17]2)[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)C.C(OC(=O)C=C(C1C=CC=C2C=1C(C#N)=[CH:40][NH:41]2)C1C=CC=CC=1)C>>[CH3:23][O:22][C:15]1[C:14]2[C:18](=[CH:19][CH:20]=[CH:21][C:13]=2[C:6]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)=[CH:5][C:4]([NH:41][CH3:40])=[O:3])[NH:17][N:16]=1참가 물질
3
실험 절차
3-(3-Methoxy-1H-indazol-4-yl)-N-methyl-3-phenyl-acrylamide CLXXXVIII was prepared from 3-(3-methoxy-1H-indazol-4-yl)-3-phenyl-acrylic acid ethyl ester using the procedure described for preparation of 3-(1H-Indol-7-yl)-N-methyl-3-phenyl-acrylamide XVIII (see Example 4).
출처 및 근거
- ORD 기록
- ord-ef1911eef11043f293d289e81fed17be
- 출처 데이터셋
- uspto-grants-2008_11