Potassium Carbonate → 3-(2',4'-Dibromo-4-biphenylyl)-3-hydroxybutyric acid

HRID 26913노트

반응식

HRID 26913 반응식
C([O:3][C:4](=[O:23])[CH2:5][C:6]([C:9]1[CH:14]=[CH:13][C:12]([C:15]2[CH:20]=[CH:19][C:18]([Br:21])=[CH:17][C:16]=2[Br:22])=[CH:11][CH:10]=1)([OH:8])[CH3:7])C.C(=O)([O-])[O-].[K+].[K+]>CO>[Br:22][C:16]1[CH:17]=[C:18]([Br:21])[CH:19]=[CH:20][C:15]=1[C:12]1[CH:13]=[CH:14][C:9]([C:6]([OH:8])([CH3:7])[CH2:5][C:4]([OH:23])=[O:3])=[CH:10][CH:11]=1

참가 물질

4

반응물 2

HCID 11430Potassium CarbonateHCID 536553833-(2',4'-Dibromo-4-biphenylyl)-3-hydroxybutyric acid ethyl ester

생성물 1

HCID 213225893-(2',4'-Dibromo-4-biphenylyl)-3-hydroxybutyric acid

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

1 g. of 3-(2',4'-dibromo-4-biphenylyl)-3-hydroxybutyric acid ethyl ester and 0.5 g. of potassium carbonate in 25 ml. of methanol are heated under reflux for one hour and the mixture is worked up to give 3-(2',4'-dibromo-4-biphenylyl)-3-hydroxybutyric acid, m.p. 118°-120°.

후처리

  1. temperatureunder reflux for one hour

출처 및 근거

ORD 기록
ord-f07fdadff2f345909745e2a263210986
출처 데이터셋
uspto-grants-1979_04
특허 번호
US04151302

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