Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium Hydroxide → 3-(2',4'-Difluoro-4-biphenylyl)-3-hydroxybutyric acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | 3-(2',4'-Difluoro-4-biphenylyl)butane-1,3-diol | HCID 21322562 | — |
| 촉매 | Silver Nitrate | HCID 24470 | — |
| 촉매 | Silver(II) oxide | HCID 92152 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 3-(2',4'-Difluoro-4-biphenylyl)-3-hydroxybutyric acid | HCID 21322583 | — |
반응 단계
Silver oxide, freshly prepared from 3.2 g. of AgNO3 and 0.8 g. of NaOH in 25 ml. of water, is added to a mixture of 2.78 g. of 3-(2',4'-difluoro-4-biphenylyl)butane-1,3-diol and 2 g. of NaOH in 20 ml. of water. The mixture is heated under reflux for 2 hours and filtered. The filtrate is worked up in the customary manner to give 3-(2',4'-difluoro-4-biphenylyl)-3-hydroxybutyric acid, m.p. 121°-123°.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04151302 |
| 출처 데이터셋 | uspto-grants-1979_04 |
| ORD ID | ord-c1d12b4e009b4caea87982793f81e86f |
| 출처 메모 | uspto-grants-1979_04 |