2,5 Dibromotoluene → 1,4-Dibromo-2-(bromomethyl)benzene

HRID 269441

반응식

HRID 269441 반응식
[Br:1]Br.[Br:3][C:4]1[CH:5]=[C:6]([CH3:11])[C:7]([Br:10])=[CH:8][CH:9]=1>>[Br:3][C:4]1[CH:5]=[C:6]([C:7]([Br:10])=[CH:8][CH:9]=1)[CH2:11][Br:1]

참가 물질

3

반응물 2

HCID 120062,5 DibromotolueneHCID 24408Bromine

생성물 1

HCID 53260381,4-Dibromo-2-(bromomethyl)benzene

실험 절차

In a three-necked round-bottom 250 ml flask equipped with a reflux condenser, thermometer, dropping funnel with pressure-equalizing, and magnetic stirring bar 15.5 ml (47.9 g, 0.30 mmol) of bromine were added dropwise to 74.9 g (0.30 mol) of 3,6-dibromotoluene under exposure to 500 W lamp for 3 h at 190° C. The resulting mixture was cooled to room temperature. Fractional distillation gave a colorless liquid, b.p. 132-135° C./3 mm Hg. Yield 84.3 g (85%).

후처리

  1. customIn a three-necked round-bottom 250 ml flask equipped with a reflux condenser
  2. distillationFractional distillation
  3. customgave a colorless liquid, b.p. 132-135° C./3 mm Hg

출처 및 근거

ORD 기록
ord-096916b32c1f4d6e911b1d588ec88e12
출처 데이터셋
uspto-grants-2008_11
특허 번호
US07446216B2

연결된 노트

불러오는 중…