Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2'-Benzyloxy-biphenyl-2-boronic acid → Ethyl 4-methyl-2''-[(phenylmethyl)oxy]-1,1':2',1''-terphenyl-2-carboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2'-Benzyloxy-biphenyl-2-boronic acid | HCID 58730990 | — |
| 반응물 | Ethyl 4-(acetylamino)-2''-[(phenylmethyl)oxy]-5''-(trifluoromethyl)-1,1':2',1''-terphenyl-2-carboxylate | HCID 58731007 | — |
| 반응물 | Ethyl 2'-bromo-4-methyl-2-biphenylcarboxylate | HCID 69309503 | — |
| 생성물 | Ethyl 4-methyl-2''-[(phenylmethyl)oxy]-1,1':2',1''-terphenyl-2-carboxylate | HCID 58730980 | — |
반응 단계
Prepared in a similar way to ethyl 4-(acetylamino)-2″-[(phenylmethyl)oxy]-5″-(trifluoromethyl)-1,1′:2′,1″-terphenyl-2-carboxylate but using {2′-[(phenylmethyl)oxy]-2-biphenylyl}boronic acid instead of [2-[(phenylmethyl)oxy]-5-(trifluoromethyl)phenyl]boronic acid and ethyl 2′-bromo-4-methyl-2-biphenylcarboxylate instead of ethyl 4-(acetylamino)-2′-bromo-2-biphenylcarboxylate. LC/MS t=4.11, [MH+] 423.1
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07446222B2 |
| 출처 데이터셋 | uspto-grants-2008_11 |
| ORD ID | ord-129eee260339493b8790589d99367e09 |
| 출처 메모 | uspto-grants-2008_11 |