Sodium Azide → HCID 57440193, 화합물

HRID 269618노트

반응식

HRID 269618 반응식
CS(O[CH2:6][C@@H:7]([NH:18][C:19]([O:21][C:22]([CH3:25])([CH3:24])[CH3:23])=[O:20])[CH2:8][CH2:9][NH:10][C:11]([O:13][C:14]([CH3:17])([CH3:16])[CH3:15])=[O:12])(=O)=O.[N-:26]=[N+:27]=[N-:28].[Na+]>CN(C)C=O>[C:14]([O:13][C:11](=[O:12])[NH:10][CH2:9][CH2:8][C@H:7]([NH:18][C:19]([O:21][C:22]([CH3:25])([CH3:24])[CH3:23])=[O:20])[CH2:6][N:26]=[N+:27]=[N-:28])([CH3:17])([CH3:16])[CH3:15]

참가 물질

4

반응물 2

HCID 33557Sodium AzideHCID 86601681(2S)-2,4-Bis[(tert-butoxycarbonyl)amino]butyl methanesulphonate

생성물 1

HCID 57440193HCID 57440193, 화합물

시약·촉매·용매 1

HCID 6228Dimethylformamide용매

실험 절차

Preparation takes place in analogy to Example 85A from 200 mg (0.52 mmol) of (2S)-2,4-bis[(tert-butoxycarbonyl)amino]butyl methanesulfonate (Example 90A) in 15 ml of dimethylformamide with 34 mg (0.52 mmol) of sodium azide. The product is reacted without further purification.

후처리

  1. customPreparation
  2. customThe product is reacted without further purification

출처 및 근거

ORD 기록
ord-ed6e1752664143da84ba51e770eab8e0
출처 데이터셋
uspto-grants-2008_11
특허 번호
US07446102B2

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