Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Phenacyl bromide → HCID 23111474, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Phenacyl bromide | HCID 6259 | — |
| 반응물 | Phenethyl bromide | HCID 7666 | — |
| 반응물 | 1-(4-Methoxyphenyl)-piperazine, dihydrochloride | HCID 2723700 | — |
| 반응물 | HCID 23111401 | HCID 23111401 | — |
| 생성물 | HCID 23111474 | HCID 23111474 | 16.7% |
반응 단계
Production Example 1 was repeated except that 1-(4-methoxyphenyl)piperazine dihydrochloride and (2-bromoethyl)-benzene were replaced with 1-(3-chloro-4-methoxymethoxyphenyl)-piperazine (924 mg) and 2-bromoacetophenone (789 mg), respectively. Thus obtained crude product was purified on silica gel column chromatography (eluent, chloroform: acetone=20:1), to provide 2-[4-(3-chloro-4-methoxymethoxyphenyl)piperazin-1-yl]-1-phenylethan-1-one (225 mg).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07449466B2 |
| 출처 데이터셋 | uspto-grants-2008_11 |
| ORD ID | ord-9285a092300e433b9772f00c2f935372 |
| 출처 메모 | uspto-grants-2008_11 |