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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 269912생성일: 2026년 10월 27일

1-(4-Methoxyphenyl)-4-phenethylpiperazine → 4-[4-(3-Cyclohexylpropyl)piperidino]-2,5-difluorophenol

https://huagongshe.com/reaction/269912

반응식

참여 물질

역할이름HCID투입량
반응물1-(4-Methoxyphenyl)-4-phenethylpiperazineHCID 15527076—
반응물4-(3-Cyclohexylpropyl)-1-(2,5-difluoro-4-methoxyphenyl)piperidineHCID 23111463—
생성물4-[4-(3-Cyclohexylpropyl)piperidino]-2,5-difluorophenolHCID 23111444253.6%

반응 단계

Production Example 2 was repeated except that 1-(4-methoxyphenyl)-4-phenethylpiperazine was replaced with 4-(3-cyclohexylpropyl)-1-(2,5-difluoro-4-methoxyphenyl)piperidine (246 mg), to provide crude 4-[4-(3-cyclohexylpropyl)piperidino]-2,5-difluorophenol (599 mg).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07449466B2
출처 데이터셋uspto-grants-2008_11
ORD IDord-df1ee3b037704b27a0d4791d3ad1df9b
출처 메모uspto-grants-2008_11