Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Phenethyl bromide → 1-(2-Cyclohexylethyl)-4-(2,5-difluoro-4-methoxyphenyl)piperazine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Phenethyl bromide | HCID 7666 | — |
| 반응물 | 1-(4-Methoxyphenyl)-piperazine, dihydrochloride | HCID 2723700 | — |
| 반응물 | 2-Cyclohexylethyl methylsulfonate | HCID 22723173 | — |
| 반응물 | 1-(2,5-Difluoro-4-methoxyphenyl)piperazine | HCID 23111492 | — |
| 생성물 | 1-(2-Cyclohexylethyl)-4-(2,5-difluoro-4-methoxyphenyl)piperazine | HCID 23111479 | — |
반응 단계
Production Example 1 was repeated except that 1-(4-methoxyphenyl)piperazine dihydrochloride and (2-bromoethyl)-benzene were replaced with 1-(2,5-difluoro-4-methoxyphenyl)-piperazine (342 mg) and 2-cyclohexylethyl methylsulfonate (309 mg), respectively, to provide crude 1-(2-cyclohexylethyl)-4-(2,5-difluoro-4-methoxyphenyl)piperazine (476 mg).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07449466B2 |
| 출처 데이터셋 | uspto-grants-2008_11 |
| ORD ID | ord-67875280920946beabd45c1e37fa0c34 |
| 출처 메모 | uspto-grants-2008_11 |