Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Isovaleryl chloride → 4-(2,5-Difluoro-4-methoxyphenyl)-1-(octylsulfonyl)piperazine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Isovaleryl chloride | HCID 66054 | — |
| 반응물 | 1-Octanesulfonyl chloride | HCID 82261 | — |
| 반응물 | 1-(4-Methoxyphenyl)-piperazine, dihydrochloride | HCID 2723700 | — |
| 반응물 | 1-(2,5-Difluoro-4-methoxyphenyl)piperazine | HCID 23111492 | — |
| 생성물 | 4-(2,5-Difluoro-4-methoxyphenyl)-1-(octylsulfonyl)piperazine | HCID 23111477 | — |
반응 단계
Production Example 3 was repeated except that 1-(4-methoxyphenyl)piperazine dihydrochloride and isovaleryl chloride were replaced with 1-(2,5-difluoro-4-methoxyphenyl)-piperazine (456 mg) and 1-octanesulfonyl chloride (470 μL), respectively, to provide crude 4-(2,5-difluoro-4-methoxyphenyl)-1-(octylsulfonyl)piperazine (681 mg).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07449466B2 |
| 출처 데이터셋 | uspto-grants-2008_11 |
| ORD ID | ord-990d7e1f09e3475ba7413660505d1012 |
| 출처 메모 | uspto-grants-2008_11 |