Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Triphenylphosphine → 3-Methyl-4-methoxybenzyl triphenylphosphonium chloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Triphenylphosphine | HCID 11776 | — |
| 반응물 | 4-Methoxy-3-methylbenzyl chloride | HCID 143742 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | 3-Methyl-4-methoxybenzyl triphenylphosphonium chloride | HCID 46180035 | 71% |
반응 단계
To a 250ml round-bottom flask equipped with a magnetic stir-bar and N2inlet was added 4-(Chloromethyl)-2-methylphenyl methyl ether (2.59g, 15.18mmoles, 1eq), dry toluene (50ml, 0.3M) and triphenylphosphine (3.98g, 15.18mmoles, 1eq). The reaction mixture was refluxed overnight. After cooling to room temperature the solvent was removed in vacuo, the residue washed with hexanes and the solid/liquid mixture was filtered to yield 4.48g (71%) of solid product.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07449468B2 |
| 출처 데이터셋 | uspto-grants-2008_11 |
| ORD ID | ord-a8fd80fb3ecd46b39c18bdf4df3422d0 |
| 출처 메모 | uspto-grants-2008_11 |