(2-Methoxyethyl)(methyl)amine → [2-[3-(4-Bromo-phenyl)-benzo[d]isothiazol-6-yloxy]-ethyl]-(2-methoxy-ethyl)-methyl-amine

반응식

Br[CH2:2][CH2:3][O:4][C:5]1[CH:20]=[CH:19][C:8]2[C:9]([C:12]3[CH:17]=[CH:16][C:15]([Br:18])=[CH:14][CH:13]=3)=[N:10][S:11][C:7]=2[CH:6]=1.[CH3:21][O:22][CH2:23][CH2:24][NH:25][CH3:26]>>[Br:18][C:15]1[CH:16]=[CH:17][C:12]([C:9]2[C:8]3[CH:19]=[CH:20][C:5]([O:4][CH2:3][CH2:2][N:25]([CH2:24][CH2:23][O:22][CH3:21])[CH3:26])=[CH:6][C:7]=3[S:11][N:10]=2)=[CH:13][CH:14]=1

참가 물질

반응물 2

HCID 300977(2-Methoxyethyl)(methyl)amine

HCID 22314138HCID 22314138, 화합물

생성물 1

HCID 22313886[2-[3-(4-Bromo-phenyl)-benzo[d]isothiazol-6-yloxy]-ethyl]-(2-methoxy-ethyl)-methyl-amine

실험 절차

According to the method in example 4, 6-(2-Bromo-ethoxy)-3-(4-bromo-phenyl)-benzo[d]isothiazole and N-(2-methoxyethyl)methylamine were converted to yield [2-[3-(4-Bromo-phenyl)-benzo[d]isothiazol-6-yloxy]-ethyl]-(2-methoxy-ethyl)-methyl-amine, MS: 422 (MH+, 1Br).

출처 및 근거

ORD 기록: ord-d7a56eaaff58462d9dddda7b180df8d3
출처 데이터셋: uspto-grants-2008_11
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07449483B2

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