Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dimethylcarbamoyl Chloride → 1-(N,N-Dimethylcarbamoyl)-4,5-dicyanoimidazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dimethylcarbamoyl Chloride | HCID 6598 | — |
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | 1,4-Dioxane | HCID 31275 | — |
| 반응물 | 4,5-Dicyanoimidazole | HCID 70729 | — |
| 생성물 | 1-(N,N-Dimethylcarbamoyl)-4,5-dicyanoimidazole | HCID 23343418 | — |
반응 단계
To 50 ml of dry 1,4-dioxane 6.0 g (0.05 mole) of 4,5-dicyanoimidazole, 5.0 g (0.05 mole) of triethylamine and 6.0 g (0.055 mole) of dimethylcarbamoyl chloride are added in succession at room temperature. This mixture is stirred and refluxed for 3 days, cooled to room temperature and evaporated to dryness. The residue is stirred in 50 ml of ethyl acetate and 50 ml water. The organic layer is separated, washed, dried and evaporated to give 8 g. (85%) of white product.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04220466 |
| 출처 데이터셋 | uspto-grants-1980_09 |
| ORD ID | ord-ccbdcc529e104ca9a8cdaf4b5e1e4621 |
| 출처 메모 | uspto-grants-1980_09 |