3-[3-(4-Chloro-phenyl)-benzo[d]isothiazol-6-yl]-prop-2-yn-1-ol → 3-[3-(4-Chloro-phenyl)-benzo[d]isothiazol-6-yl]-propan-1-ol

HRID 270367노트

반응식

HRID 270367 반응식
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[C:12]3[CH:13]=[CH:14][C:15]([C:17]#[C:18][CH2:19][OH:20])=[CH:16][C:11]=3[S:10][N:9]=2)=[CH:4][CH:3]=1>CCO.O1CCOCC1>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[C:12]3[CH:13]=[CH:14][C:15]([CH2:17][CH2:18][CH2:19][OH:20])=[CH:16][C:11]=3[S:10][N:9]=2)=[CH:6][CH:7]=1

참가 물질

3

반응물 1

HCID 223139063-[3-(4-Chloro-phenyl)-benzo[d]isothiazol-6-yl]-prop-2-yn-1-ol

생성물 1

HCID 223141453-[3-(4-Chloro-phenyl)-benzo[d]isothiazol-6-yl]-propan-1-ol

시약·촉매·용매 1

HCID 22560076Dioxan ethanol용매

실험 절차

In analogy to example 20.1, 3-[3-(4-Chloro-phenyl)-benzo[d]isothiazol-6-yl]-prop-2-yn-1-ol in EtOH/dioxane was converted to yield 3-[3-(4-Chloro-phenyl)-benzo[d]isothiazol-6-yl]-propan-1-ol as a brown oil, MS: 303 (M, 1Cl).

출처 및 근거

ORD 기록
ord-c9fb1a7996ad4f8883f5d490473d0af1
출처 데이터셋
uspto-grants-2008_11
특허 번호
US07449483B2

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