Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ticlopidine → 4,5,6,7-Tetrahydrothieno(3,2-c)pyridine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ticlopidine | HCID 5472 | — |
| 반응물 | Thiopheneethanamine | HCID 116521 | — |
| 생성물 | 4,5,6,7-Tetrahydrothieno(3,2-c)pyridine | HCID 3085076 | — |
반응 단계
Alternatively, ticlopidine of formula (1a) may also be synthesized by directly cyclizing 2-(2-aminoethyl)thiophene of formula (a) with a formylating agent to obtain 4,5,6,7-tetrahydrothieno[3,2-c]pyridine of formula (f), and then reacting the compound (f) with a compound of formula (b).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07449580B2 |
| 출처 데이터셋 | uspto-grants-2008_11 |
| ORD ID | ord-8918957f0be54d69b3276552a895d2b6 |
| 출처 메모 | uspto-grants-2008_11 |