참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Dimethylformamide | HCID 6228 | — |
| 반응물 | Chlorosuccinimide | HCID 31398 | — |
| 반응물 | 1H-Pyrazole, 3-methyl-5-(trifluoromethyl)- | HCID 139077 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | HCID 178434610 | HCID 178434610 | — |
반응 단계
3-methyl-5-trifluoromethylpyrazole was taken into dry DMF (20 mL) and N-chloro succinimide (1.78 g) was added in portions. The mixture was then heated at 70° C. for 22 h, cooled to room temperature, and then water (100 mL) was added and the mixture extracted with ethyl acetate (4×25 mL). The organic layer was washed with water and brine and dried with Na2SO4. Evaporation of the solvent afforded the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US07449576B1 |
|---|
| 출처 데이터셋 | uspto-grants-2008_11 |
|---|
| ORD ID | ord-54f8eead3ef64bd1b4ef90c1484c3d55 |
|---|
| 출처 메모 | uspto-grants-2008_11 |
|---|
