Water → 1-Ethenyl-2-(iodomethyl)benzene

HRID 2709

반응식

HRID 2709 반응식
Cl[CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[CH:9]=[CH2:10].[I-:11].[Na+].O>CC(C)=O>[I:11][CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[CH:9]=[CH2:10]

참가 물질

5

반응물 3

HCID 962WaterHCID 5238Sodium IodideHCID 897571-(Chloromethyl)-2-ethenylbenzene

생성물 1

HCID 158305741-Ethenyl-2-(iodomethyl)benzene수율 95%

시약·촉매·용매 1

HCID 180Acetone용매

실험 절차

Dissolve 1-chloromethyl-2-vinyl-benzene (4.0 g, 26 mmol) in acetone (100 mL) and add sodium iodide (4.5 g, 30 mmol). Heat at gentle reflux for 30 minutes. Cool, add water (150 mL) and extract with pentane (200 mL). Dry (MgSO4) and evaporate the solvent in vacuo to give the title compound (95%).

후처리

  1. temperatureHeat
  2. temperatureat gentle reflux for 30 minutes
  3. temperatureCool
  4. extractionextract with pentane (200 mL)
  5. dry with materialDry (MgSO4)
  6. customevaporate the solvent in vacuo

출처 및 근거

ORD 기록
ord-e62ed52d8b364ce5b8047d942697fb19
출처 데이터셋
uspto-grants-1998_03
특허 번호
US05731306

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