Hydrazine → HCID 22353179, 화합물
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C([O:3][C:4](=O)[CH2:5][C:6](=O)[C:7]1[CH:12]=[C:11]([O:13][CH3:14])[C:10]([O:15][CH3:16])=[C:9]([O:17][CH3:18])[CH:8]=1)C.[NH2:21][NH2:22]>C(#N)C>[CH3:18][O:17][C:9]1[CH:8]=[C:7]([C:6]2[CH2:5][C:4](=[O:3])[NH:21][N:22]=2)[CH:12]=[C:11]([O:13][CH3:14])[C:10]=1[O:15][CH3:16]참가 물질
4
실험 절차
To a stirred solution of 3-oxo-3-(3,4,5-trimethoxyphenyl)-propionic acid ethyl ester (2.82 g, 10 mmol) in dry acetonitrile (15 mL) was added to anhydrous hydrazine (640 mL, 20 mmol) at room temperature. After 1 hour, the mixture was heated to reflux for 16 hours. The mixture was diluted with acetonitrile (20 mL) and the solid was filtered. The solid was washed with acetonitrile (10 mL) and dried under nitrogen to afford 2.2 g of title compound (k).
후처리
- temperaturethe mixture was heated
- temperatureto reflux for 16 hours
- filtrationthe solid was filtered
- washThe solid was washed with acetonitrile (10 mL)
- customdried under nitrogen
출처 및 근거
- ORD 기록
- ord-c7d9bdb79795433886ab3fe7521e992a
- 출처 데이터셋
- uspto-grants-2008_11
- 특허 번호
- US07452873B2
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