2-Chloro-5-(chloromethyl)pyridine → 4-[1-(2-Chloro-pyridin-5-ylmethyl)-2-methyl-1H-imidazol-4-ylethynyl]-2-chloro-pyridine

HRID 271502

반응식

HRID 271502 반응식
[Cl:1][C:2]1[CH:7]=[C:6]([C:8]#[C:9][C:10]2[N:11]=[C:12]([CH3:15])[NH:13][CH:14]=2)[CH:5]=[CH:4][N:3]=1.[Cl:16][C:17]1[CH:22]=[CH:21][C:20]([CH2:23]Cl)=[CH:19][N:18]=1>>[Cl:16][C:17]1[CH:22]=[CH:21][C:20]([CH2:23][N:13]2[CH:14]=[C:10]([C:9]#[C:8][C:6]3[CH:5]=[CH:4][N:3]=[C:2]([Cl:1])[CH:7]=3)[N:11]=[C:12]2[CH3:15])=[CH:19][N:18]=1

참가 물질

3

반응물 2

HCID 1554792-Chloro-5-(chloromethyl)pyridineHCID 178418879HCID 178418879, 화합물

생성물 1

HCID 112100724-[1-(2-Chloro-pyridin-5-ylmethyl)-2-methyl-1H-imidazol-4-ylethynyl]-2-chloro-pyridine

실험 절차

The title compound, MS: m/e=343.1 (M+H30), was prepared in accordance with the general method of example 1 from 2-chloro-4-(2-methyl-1H-imidazol-4-ylethynyl)-pyridine and 2-chloro-5-chloromethyl-pyridine.

출처 및 근거

ORD 기록
ord-4cb2c447c3eb4fa09679d66f86bbd6e6
출처 데이터셋
uspto-grants-2008_11
특허 번호
US07452909B2

연결된 노트

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