3,4-Dichloroaniline → N-(3,4-dichlorophenyl)dimethyl-maleimide

HRID 27185

반응식

HRID 27185 반응식
[CH3:1][C:2]1=[C:3]([CH3:9])[C:4]([O:6][C:7]1=O)=[O:5].[Cl:10][C:11]1[CH:12]=[C:13]([CH:15]=[CH:16][C:17]=1[Cl:18])[NH2:14]>>[Cl:10][C:11]1[CH:12]=[C:13]([N:14]2[C:7](=[O:6])[C:2]([CH3:1])=[C:3]([CH3:9])[C:4]2=[O:5])[CH:15]=[CH:16][C:17]=1[Cl:18]

참가 물질

3

반응물 2

HCID 72573,4-DichloroanilineHCID 13010Dimethylmaleic anhydride

생성물 1

HCID 23343685N-(3,4-dichlorophenyl)dimethyl-maleimide

실험 절차

In a manner analogous to that of Example 2, 26.2 g (0.2 mole) of dimethylmaleic acid anhydride and 32.6 g (0.2 mole) of 3,4-dichloroaniline are condensed to give N-(3,4-dichlorophenyl)-dimethyl-maleimide, which is then dissolved in 300 ml of methanol. To this solution is slowly added in portions, with stirring, 10.8 g of sodium borohydride. After the addition is complete and the generation of gas has subsided, the reaction mixture is poured into ice water. The white precipitate is filtered off, washed with methanol and dried. There is obtained 49.3 g (84% of theory) of the above product in the form of colourless crystalline powder, m.p. 188°.

후처리

  1. customcondensed

출처 및 근거

ORD 기록
ord-18d7dcb67c4e49dfbf9f006422306ab9
출처 데이터셋
uspto-grants-1980_09
특허 번호
US04220655

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