tert-Butyl isocyanate → 1-(2,6-Dichlorophenyl)3-(t-butylcarbamyl)thiourea
반응식
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([Cl:8])[C:3]=1[NH:9][C:10]([NH2:12])=[S:11].[C:13]([N:17]=[C:18]=[O:19])([CH3:16])([CH3:15])[CH3:14]>C1(C)C(C)=CC=CC=1>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([Cl:8])[C:3]=1[NH:9][C:10]([NH:12][C:18](=[O:19])[NH:17][C:13]([CH3:16])([CH3:15])[CH3:14])=[S:11]참가 물질
4
실험 절차
To a mixture of 11 g (0.05 mole) of 1-(2,6-dichlorophenyl)thiourea and 10 ml of xylene is added 5 g of t-butylisocyanate (0.05 mole) and the mixture is refluxed for 2 hours. The reaction product is cooled, triturated with heptane and filtered. Recrystallization from 1:1 isopropanol/water results in 1-(2,6-dichlorophenyl)-3-(t-butylcarbamyl)thiourea.
후처리
- temperaturethe mixture is refluxed for 2 hours
- temperatureThe reaction product is cooled
- customtriturated with heptane
- filtrationfiltered
- customRecrystallization from 1:1 isopropanol/water
- customresults in 1-(2,6-dichlorophenyl)-3-(t-butylcarbamyl)thiourea
출처 및 근거
- ORD 기록
- ord-40a28be1546348e08f09ece6b171d0f0
- 출처 데이터셋
- uspto-grants-1980_09
- 특허 번호
- US04220658
반응 노트
불러오는 중…