Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-[(Thiazol-2-yl)methylthio]ethylamine → 3-[2-(2-Thiazolylmethylthio)ethylamino]-6-(3-methoxybenzyl)-1,2,4-triazin-5-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-[(Thiazol-2-yl)methylthio]ethylamine | HCID 12923403 | — |
| 반응물 | 3-Methylthio-6-(3-methoxybenzyl)-1,2,4-triazin-5-one | HCID 135624292 | — |
| 생성물 | 3-[2-(2-Thiazolylmethylthio)ethylamino]-6-(3-methoxybenzyl)-1,2,4-triazin-5-one | HCID 135703224 | 47.6% |
반응 단계
3-Methylthio-6-(3-methoxybenzyl)-1,2,4-triazin-5-one (1.18 g) and 2-(2-thiazolylmethylthio)ethylamine (0.87 g) were heated together on an oil bath (160°-70°) for 3/4 hour. The resulting oil, after chromatography and crystallisation from ethanol, gave the title compound as a colourless solid (0.83 g) m.p. 128°-29°.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04220767 |
| 출처 데이터셋 | uspto-grants-1980_09 |
| ORD ID | ord-91e47578093249e3a13d72b35c15fd5b |
| 출처 메모 | uspto-grants-1980_09 |