참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Aripiprazole | HCID 60795 | — |
| 용매 | 1,2-Dichloroethane | HCID 11 | — |
| 생성물 | Aripiprazole ethylenedichloride | HCID 11489682 | 136.5% |
반응 단계
Aripiprazole (3 gm) is mixed with ethylenedichloride (30 ml) and heated to 50° C. to form a clear solution. The solution is slowly cooled to 25° C., stirred for 1 hour at about 25° C. and the separated crystals are collected by filtration to give 2.5 gm of aripiprazole ethylenedichloride solvate form V.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US07456181B2 |
|---|
| 출처 데이터셋 | uspto-grants-2008_11 |
|---|
| ORD ID | ord-96181f3c68c34f33896c55e67d1d75aa |
|---|
| 출처 메모 | uspto-grants-2008_11 |
|---|
