4-Morpholinophenol → 1-(4-chloro-2-methoxybenzyl)pyridin-4(1H)-one

반응식

[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8]O)=[C:4]([O:10][CH3:11])[CH:3]=1.[N:12]1[CH:17]=[CH:16][C:15]([OH:18])=[CH:14][CH:13]=1.O1CCN(C2C=CC(O)=CC=2)CC1>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][N:12]2[CH:17]=[CH:16][C:15](=[O:18])[CH:14]=[CH:13]2)=[C:4]([O:10][CH3:11])[CH:3]=1

참가 물질

반응물 3

HCID 805104-Morpholinophenol

HCID 35493934 Chloro-2-methoxybenzyl alcohol

HCID 178418642HCID 178418642, 화합물

생성물 1

HCID 692195151-(4-chloro-2-methoxybenzyl)pyridin-4(1H)-one

실험 절차

The title compound was prepared by substituting (4-chloro-2-methoxy-phenyl)-methanol and pyridin-4-ol for Example 204A and 4-morpholinophenol, respectively, in Example 297A. MS (ESI) m/e 250 (M+H)+.

출처 및 근거

ORD 기록: ord-0fa817a67a7147b1a7211b1a3fa41fe9
출처 데이터셋: uspto-grants-2008_11
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07456169B2

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