Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-[4-(1-Isopropylpiperidin-4-yloxy)phenyl]tetrahydropyran-4-carbonitrile → 4-{4-[(1-isopropylpiperidin-4-yl)oxy]phenyl}tetrahydro-2H-pyran-4-carbothioamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-[4-(1-Isopropylpiperidin-4-yloxy)phenyl]tetrahydropyran-4-carbonitrile | HCID 11500842 | — |
| 반응물 | Diethyldithiophosphate | HCID 53249491 | — |
| 생성물 | 4-{4-[(1-isopropylpiperidin-4-yl)oxy]phenyl}tetrahydro-2H-pyran-4-carbothioamide | HCID 86601902 | 74% |
반응 단계
The title compound (320 mg, 74%) was prepared from 4-[4-(1-isopropylpiperidin-4-yloxy)phenyl]tetrahydropyran-4-carbonitrile and diethyl dithiophosphate similarly to the procedure used for intermediate 50. LRMS APCI+ m/z 363 [MH]+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07456164B2 |
| 출처 데이터셋 | uspto-grants-2008_11 |
| ORD ID | ord-e82aa4813a064554b0dcb3babcd4d819 |
| 출처 메모 | uspto-grants-2008_11 |